Is there a day treatment program he can go to, where they offer social skills training and hygiene training?. Perhaps if he has some outside people that depend on him to show up clean and ready to go, perhaps over time his hygiene will improve. I understand your plight. I am bipolar, but I have never gotten like your son. However, my brother who is also bipolar, has terrible hygiene just like your son. From someone who has come from both sides of the fence, I just want to validate your feelings and tell you that your feelings are normal too. Perhaps there is a support group nearby that you can attend? Try NAMI - National Alliance of the Mentally Ill. They have some great resources for families as well as clients.