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Originally Posted by -jimi-
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Ah thanks - so not the study I linked to (which is later and seems more balanced)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471960/
Can't access the full Finnish paper but this statement seems on the face of it to be highly questionable and you would think needs further analysis:
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The Finnish study found no pronounced differences in heart deaths between the different atypicals, but patients on clozapine had a substantially lower risk of suicide while those on Seroquel were more likely to kill themselves.
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Thing is typically in modern practice this may simply reflect patterns of prescribing, generally Seroquel (or similar atypicals) would be the treatment of choice for first episode and acute psychosis, which I would have thought are more likely to be riskier in terms of suicide risk anyway than people who are on longer term management for chronic psychotic conditions like Schizophrenia, who may still be on some of the older antipsychotics but who would, by definition, be 'better managed' and overall less of a suicide risk.