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Old 01-07-2019, 06:16 PM  
OliverB
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Default Re: Surviving Anhedonia

Have you ever tried st john's wort?

It inhibits dopamine, serotonine, norepinephrine, GABA and glutamate reuptake and has a mild MAOI effect (so you have more of everything), lower inflammatory responses and regulates the cortisol axis. I have found myself more driven to do things while taking it, even if emotionally I don't feel well. It doesn't cause sexual dysfunction as far as I know, It's totally different from any synthetic antidepressant.

It interacts with a lot of meds so if you want to try it you need to ask a doctor first.

Also, there is tianeptine that regulates the glutamate neurotransmission and has some opioid-like activity, It is not approved in all countries.

SSRI and AP caused me severe anhedonia while I was a teen, it took me 3-4 years to recover some normal emotions. Now my depression is "normal" depression (negative emotions) instead of absolutely nothingness about everything (actually, I think it is also the reason why I was so schizoid-like and never had any kind of interest towards my peers, sexual or social interest). I think I haven't fully recovered yet, I don't know if it is even possible since the damage was done while I was a teen.
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Last edited by OliverB; 01-07-2019 at 06:31 PM..
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