Yes, I've definitely seen a difference with her being on the insulin, just with a few days. She's drinking less water and I haven't seen her have any accidents, though that was the bladder infection and the antibiotics should be clearing that up. Just she isn't eating very much and if she doesn't eat she can't get the insulin. I'm going to work with her through the weekend, and if it isn't much better I'm going to talk to the vet about how to transition her food. Thank you Travelinglady. Kit