If I wake up feeling pretty level, I can get away with having 2 10oz cups of java. But if I feel anxiety or mania kicking in, then it's usually just one I stick to (or sometimes none). In the past, though, I've been known to have 3-4 but my doc seriously wants me to cut down. If I do have a third, it's no later than 2-3pm, and that's only if my meds keep me feeling sedated or sluggish. which they have been known to do. I would listen to your body, though, and if you get regulated to the meds and can get away with one cup, then go for it! good luck!