My sister finds it helpful for mild unipolar depression. She does not take medication. I read that it is more helpful for mild-mod as opposed to severe but I'm no expert.
Always good to consult with a herbalist or naturopath because those herbal options can still be potent and they are not regulated by the FDA. Last time I checked they weren't anyway. And yes, as Bird Dancer pointed out, it could interact with other meds.