hi. EPS is short for extra-pyramidal (I think...) symptoms or something...its when you get muscle stiffness, stiff gait, dystonic reactions, etc. its the acute/short and mid term reaction. tardive syndromes sometimes develop later on in treatment, more often with the older drugs.

i think all antipsychotics block D2. if its blocked to a point, mania and Schizophrenia get better. blocked too much, EPS. blocked too much for a long time, tardive syndromes. deal with Abilify is that it takes over the D2 receptor, so it blocks it but also partially, mildly stimulates it...so you (ideally, if it works out) get rid of mania, get control over Schizophrenia, but don't get EPS, hopefully no tardive syndromes.

Vraylar is the same way ("D2 Partial Agonist"), but it doesn't stimulate the D2 receptor as much, so its more just straight up blocking it. ugh. not excited.