Most depression meds have not been evaluated for long term use. We don't know for sure what the long term effects may be. There is growing evidence that they cause long term sexual side effects, even after discontinuation. So I think that is one reason people want to get off of them-just because we don't know what long term effects might be. Also, there is growing evidence that the longer you take them, the harder it is to get off. For me, it was because they don't work. So I guess I can't really answer your question.