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Originally Posted by Moose72
I think ZzzQuil is just Benadryl- both are diphenhydramine. Would you take Benadryl with other sedating meds? I did that once- took Benadryl with Seroquel and was noticeably sedated, so that's probably a bad idea to take ZzzQuil with your PRN.
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Benadryl works on some of the same neuroreceptors as other psych meds. I'd be concerned about throwing that out of balance more than anything. The working theory is that most psych meds are effective when the levels are constant. And obviously the dosing matters. Mixing these kinds of meds can be dangerous for various reasons.