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Old 09-15-2020, 11:21 AM   #11
BethRags
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Default Re: Zzquil and benzos?

I take ZzzQuil almost every night. I have absolutely no problem with combining it with my meds, including Klonopin. I've never met any pdoc who cautions against taking diphenhydramine with psych meds. In fact, many of them have encouraged taking OTC sleep medication - just not for a long period of time.

My pdoc did tell me not to take ZzQuil every night because it can cause a drop in blood pressure (she's kind-of obsessed with her patients not falling when they stand up). But I've been taking it every night & now I can't sleep without it
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Old 09-15-2020, 06:32 PM   #12
Moose72
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Default Re: Zzquil and benzos?

I think ZzzQuil is just Benadryl- both are diphenhydramine. Would you take Benadryl with other sedating meds? I did that once- took Benadryl with Seroquel and was noticeably sedated, so that's probably a bad idea to take ZzzQuil with your PRN.
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Old 09-15-2020, 07:50 PM   #13
BethRags
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Default Re: Zzquil and benzos?

Well, I asked my pdoc again today about taking ZzzQuil and she seems fine with it. Before she cautioned me about taking it every night because of the blood pressure drop thing. So, good. I'm getting the best sleep I've had in years with the low-dose Seroquel/ZzzQuil. I hope it doesn't cause an overdose . I don't think it will. I've taken diphenhydramine for allergies before (while on psych meds) and all that happened was my nose got dry and I felt sleepy.
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Old 09-16-2020, 06:08 AM   #14
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Default Re: Zzquil and benzos?

Quote:
Originally Posted by Moose72 View Post
I think ZzzQuil is just Benadryl- both are diphenhydramine. Would you take Benadryl with other sedating meds? I did that once- took Benadryl with Seroquel and was noticeably sedated, so that's probably a bad idea to take ZzzQuil with your PRN.
Benadryl works on some of the same neuroreceptors as other psych meds. I'd be concerned about throwing that out of balance more than anything. The working theory is that most psych meds are effective when the levels are constant. And obviously the dosing matters. Mixing these kinds of meds can be dangerous for various reasons.
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