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Buspar (buspirone)

Overall Rating
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2.14
Rating:

2.14

**
(Out of 5 Stars)
Side Effects
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2.81
Pricing
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3.78
Average Price: $9.06 Thumbs down Recommended By
48% of reviewers (of 44 reviews)
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Buspar®

Generic Name: Buspirone byoo-SPYE-rone

Drug Class: Sedatives/Hypnotics

 

Contents

 

Description
This medicine is a sedative which is used to help people with sleeping problems (such as trouble falling asleep, trouble staying asleep during the night, or waking too early in the morning). This medicine may be prescribed for other conditions as determined by your doctor.
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General Information
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider. 

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Proper use of this medicine
Take this medicine exactly as directed. It may be taken with food or milk if stomach upset occurs. The extended-release tablet should be swallowed whole. Do not chew, divide, or crush the extended-release tablet.
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Missed Dose
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
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Storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed.
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Possible Side Effects
    • If any of these effects persist or worsen, inform your doctor promptly:
      • stomach upset
      • blurred vision
      • headache
      • dizziness
      • depression
      • impaired coordination
      • memory loss
      • hangover effect or clouded thinking may occur
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Warnings/Precautions
    • This medicine may cause drowsiness.
    • Alcoholic beverages can increase the effects of this medicine and should be avoided.
    • Be cautious when driving or performing other hazardous activities. This medicine can impair judgment.
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Overdose
Seek medical attention immediately. U.S. residents can call the national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
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Drug Interactions
    • Possible drug interactions may occur with other sedating medications or pain medications.
    • Talk to your doctor if you are taking any medications for depression, pain, or seizures. Other sedative medications including over-the-counter antihistimines can increase the side effects of this medicine and should be used cautiously.

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Pregnancy/Nursing
If you are pregnant or thinking of becoming pregnant, talk to your doctor about the benefits and the risks of taking this edicine during your pregnancy. This medicine is excreted in breast milk. Do not breastfeed while taking this medicine.
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More Information

For more information about this medicine, talk to your healthcare provider.
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Copyright © 2006 PharmClips, Inc. All rights reserved. www.pharmclips.com
This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.



Last reviewed:

  On 8 Aug 2006

  By John M. Grohol, Psy.D.



 

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Reviews
 
klh90
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New Member

Registered: January 2019
Location: Central Arkansas
Posts: 6
Thu January 24, 2019 Recommended? Yes | Total Spent: None indicated| Rating: 6 

 
PROS: Short acting 5-HT1A partial antagonist (which, I think, not sure, helps neural changes that are reflective of antidepressant treatment)
CONS: Lots of weird side effects, requires multiple dosing and for lots of people has a limited time of efficacy (from what I've observed)

This drug was prescribed to me during college after a rather abrupt discontinuation of low dose clonazepam (and I still think I'd have graduated had I not been treated like a drug seeker). I was not happy about this, so my observation was kinda skewed, but it ended up being a very helpful drug. It increased my appetite, which was a good thing because I had lost around 30 pounds in a 2 month period because eating in a cafeteria was hard. It had some interesting interactions with my other meds, I was taking Vyvanse for ADHD and the buspar both inhibited its efficacy and enhanced it; to clarify, if I took a large dose (and I was RXed 60 mg) at night, say 30mg qhrs instead of 15 mg qid, and didn't take a dose first thing in the AM, my vyvanse would have an increased effect on my attention span and motivation without any additional anxiogenic effects. However, if I took even 15mg first thing in the AM with my vyvanse, it would blunt those effects (and presumably blunt some of the anxiogenic effects of amphetamine as well). I think these effects are due to buspirones ability to block dopamine, and its main active metabolite being an antagonist of adrenaline receptors- so a large dose qhrs would sensitize these receptors, and buspar's short duration of activity means that there is no lingering drug left on the receptor to block DA and NorAD (also some more complicated effects on the DA and NA systems via the down regulation of serotonin 1A receptor). It definitely increased the antidepressant effects of the Zoloft I was co-prescribed, helped me sleep and helped a modest amount with my social anxiety. It wasn't the best medicine, but if benzodiazepines were Legitimately off the table for someone, I'd recommend this medicine.

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Anatta
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Member

Registered: July 2018
Location: Everywhere and nowhere
Posts: 75
Tue July 31, 2018 Recommended? No | Total Spent: None indicated| Rating: 2 

 
PROS: Has no side effects....
CONS: but also does nothing...

Not much else to say. It was basically a placebo for me.

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surfzulu
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Member

Registered: March 2018
Location: Atlanta, Ga
Posts: 34
Sat April 21, 2018 Recommended? Yes | Total Spent: $10.00| Rating: 10 

 
PROS: took my severe panic attacks completely away.
CONS: None

Did what xanax could not for panic attacks kept them from starting in the first place.

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moodswings70
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Member

Registered: November 2016
Location: in a house
Posts: 39
Sat November 19, 2016 Recommended? Yes | Total Spent: $8.00| Rating: 9 

 
PROS: doesn't make you real drowsy.
CONS:

I've been on Buspar for 8 years now. I have taken it with Lexapro and now with Viibryd. It works well to keep my anxiety under control and it does not make me real tired. I take one pill in the middle of the day with lunch. I get a little drowsy, but it isn't bad at all. I take two pills at night. I do get a little more drowsy, but that is good cause it helps me sleep. I do not feel drugged or like I can't wake up in the morning.

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Erik456
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Member

Registered: May 2015
Location: LA
Posts: 79
Wed May 20, 2015 Recommended? Yes | Total Spent: None indicated| Rating: 0 

 
PROS: it works
CONS: none

I frequently order recommended drugs through americantrustpills (seriously, this place sucks) free of danger. Sad to say I use to take tons of it so low price is pretty important for me.

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katz7759
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New Member

Registered: February 2015
Location: Dallas
Posts: 4
Sun February 22, 2015 Recommended? Yes | Total Spent: $15.00| Rating: 8 

 
PROS: keeps my anxiety more low leveled, no severe panic attacks while on it
CONS: takes several weeks to build up in your system, no immediate relief when starting it

Helps keep my anxiety more under control. No major panic attacks on it. Have been taking it for 6-7 yrs.

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lilacsmoke
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Member

Registered: October 2014
Location: Canada
Posts: 53
Thu November 6, 2014 Recommended? No | Total Spent: None indicated| Rating: 1 

 
PROS: None.
CONS: Made absolutely no difference.

This medication was literally nothing more than a waste of time. It had absolutely no impact on me, for better or worse.

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HolisticGal
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Member

Registered: September 2014
Location: Western United States
Posts: 148
Fri October 17, 2014 Recommended? No | Total Spent: $5.00| Rating: 1 

 
PROS: Not a benzo
CONS: Risk of TD which can become permanent and withdrawal when quitting cold turkey.

Had withdrawal when quit cold turkey.

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misskrome
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Member

Registered: January 2014
Location: ...
Posts: 229
Sun January 19, 2014 Recommended? Yes | Total Spent: None indicated| Rating: 1 

 
PROS: none
CONS: ? something

I don't remember much about this one, other than waking up back in the hospital. That was after the first few doses.

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dillpickle1983

Grand Poohbah

Registered: January 2011
Location: Warren, Pennsylvania
Posts: 1705
Sun November 3, 2013 Recommended? No | Total Spent: None indicated| Rating: 2 

 
PROS: None
CONS: Did nothing for me

Did nothing for my anxiety, however my roommate swears by it. I guess its an individual thing.

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1948kate

Member

Registered: May 2013
Location: Nebraska
Posts: 71
Sun September 1, 2013 Recommended? Yes | Total Spent: $3.00| Rating: 4 

 
PROS: No side effects
CONS: Very mild augmentation for other medications

No side effects. Using to augment antidepressant

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usehername

Veteran Member

Registered: October 2012
Location: in my head
Posts: 542
Sun September 1, 2013 Recommended? No | Total Spent: $5.00| Rating: 1 

 
PROS: no side effects
CONS: not effective

Useless. Completely useless. Once went off of it without a taper and barely noticed the difference. That's saying a lot, don't ya think???

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SideCrow
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Member

Registered: June 2013
Posts: 68
Thu June 27, 2013 Recommended? No | Total Spent: $2.00| Rating: 1 

 
PROS: Nothing
CONS: Total anxiety while taking it. Paradoxical reaction.

Nothing good for me. 10mg twice a day for 8 days produced wicked anxiety. There's nothing else really I can point it too. I might try it again once more just to be sure, but definitely not helping.

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kaliope

Legendary Wise Elder

Registered: June 2011
Location: somewhere, out there
Posts: 36240
Thu May 2, 2013 Recommended? Yes | Total Spent: None indicated| Rating: 10 

 
PROS: works great for my anxiety
CONS: none

this med works great at controlling my anxiety with no side effects

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Thu May 2, 2013 Recommended? No | Total Spent: $10.00| Rating: 2 

 
PROS: ____
CONS: does nothing for anxiety

Does zero for anxiety.

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RedBarchetta
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Member

Registered: March 2013
Location: Moonachie, NJ
Posts: 290
Wed May 1, 2013 Recommended? Yes | Total Spent: $1.10| Rating: 7 

 
PROS: Keeps you calm without causing drowsiness
CONS: After talking it a while, large doses may be required

I have been using it for 25 years, had to increase the dose a few times, but it's still working.

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unstuckintime
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New Member

Registered: May 2012
Location: Tralfamadore
Posts: 2
Sun June 17, 2012 Recommended? No | Total Spent: None indicated| Rating: 3 

 
PROS:
CONS: increases anxiety, causes drowsiness, doesn't work

My GP prescribed buspar PRN for anxiety. It didn't help. After taking it I would feel even more nervous. I would take it sometimes to help me fall asleep, but I stopped doing that when the anxiety it caused became too great.

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hobgoblins
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New Member

Registered: November 2008
Location: Sacramento
Posts: 3
Sat April 14, 2012 Recommended? Yes | Total Spent: $5.00| Rating: 10 

 
PROS: Makes me happier
CONS: Tolerance kind of builds

Very helpful for general anxiety as well as mood!

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Lacelly
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Member

Registered: October 2010
Location: USA
Posts: 209
Sat March 31, 2012 Recommended? No | Total Spent: None indicated| Rating: 2 

 
PROS: None that I noticed
CONS: Gave me gas

Didn't do anything for my anxiety, just made me fart all the time.

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minaque
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New Member

Registered: February 2009
Location: NH
Posts: 3
Fri April 29, 2011 Recommended? Yes | Total Spent: None indicated| Rating: 9 

 
PROS: works great for me as an antidepressant .
CONS: slight effects on sleep patterns

1st antideppresant of many that worked for me.

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PaulsonLaw
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Account Suspended

Registered: October 2009
Posts: 63
Sun October 25, 2009 Recommended? No | Total Spent: $3.00| Rating: 3 

 
PROS: none towards anziety
CONS: memory loss, not able to muti task

Not able to muti task & severe loss of memory. Of course maybe this is a good thing for OCD or Abused person. Not for me.

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tigerm
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Newly Joined

Registered: August 2009
Sun August 23, 2009 Recommended? Yes | Total Spent: $7.00| Rating: 10 

 
PROS: It works
CONS: drowsiness

Good anxiolitic.

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tigerm
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Newly Joined

Registered: August 2009
Sun August 23, 2009 Recommended? Yes | Total Spent: $7.00| Rating: 9 

 
PROS: Antianxiety/sleep
CONS: drowsiness

Primary use of this drug is for antianxiety, not as a sedative/hypnotic. It is an anxiolitic that is commonly used in place of ativan as a non addictive med. I'm not sure why they have it listed as sedative/hypnotic. Even the manufacturer has a different take on the med. Regardless, I have found it quite helpful in alleviating my panic attacks and PTSD symptoms.

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ks5891
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Newly Joined

Registered: March 2009
Sat March 7, 2009 Recommended? Yes | Total Spent: None indicated| Rating: 9 

 
PROS: sense of wellbeing, reduced anxiety over little things
CONS: bit of too much chillout

Wow! Buspirone has so far been a great help to me. I have been taking fluoxetine (Prozac) for 2 years and well lately it has lost all of its inital benefits. My doc recommended giving Buspar a try. I do not know if it's Prozac-back-online or buspirone alone, but I definately feel like something has pressed the right buttons in my brain and my anxiety is withdrawing. I've understood that many people find buspirone useless which is a shame. It might be that buspirone needs an SSRI in order to exert any effect, on the other hand I have generalized anxiety and buspirone works the best against this ailment. Seriously people this drug is highly selective and working in the field of molecular biology I must admit that this thing by mechanism is just made for killing anxiety (even the slight D2 antagonism is necessary IMO).

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HALLIEBETH87

Wise Elder

Registered: October 2004
Location: usa
Posts: 9069
Wed August 20, 2008 Recommended? Yes | Total Spent: $40.00| Rating: 7 

 
PROS: 0 panic attacks
CONS: memory loss

I was shocked that it actually helped me. I take the 15 mg 4x a day...that might be why. I cannot remember my last panic attack.

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lv701

Newly Joined

Registered: March 2008
Tue June 24, 2008 Recommended? Yes | Total Spent: None indicated| Rating: 5 

 
PROS: helped wiyh anxiety
CONS: none

helped me with my anxiety

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psychydoc
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New Member

Registered: June 2008
Posts: 2
Tue June 3, 2008 Recommended? No | Total Spent: None indicated| Rating: 1 

 
PROS: Placebo effect maybe???
CONS: Didn't work

I was on this medication for about 6 months and I still am not sure if it worked, don't believe so. I eventually got on Klonopin for anxiety because my panic attacks were too severe and buspirone didn't work immediatley to help anxiety attacks.

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sunshinesqrrl

New Member

Registered: April 2007
Location: Rehoboth Beach, DE
Posts: 1
Fri April 4, 2008 Recommended? No | Total Spent: $3.00| Rating: 3 

 
PROS: made me a little high
CONS: shakes, no real relief

it was not sufficient to control my anxiety and I had some memory loss and insomnia

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kabluie

Junior Member

Registered: January 2008
Location: East Coast, U.S.
Posts: 8
Thu January 17, 2008 Recommended? Yes | Total Spent: None indicated| Rating: 8 

 
PROS: effective for me at higher doses
CONS: nausea, dizziness (infrequent)

I thought this med was worthless and my p-doc crazy (ha ha) until she boosted my dose up to the higher limits (above 50 mg/day). Bingo! I now take it in three doses a day, and am finding myself considerably less anxious. I've had anxiety problems--serious problems--for nearly 20 years and have only found this level of relief with benzos in the past, taken in a reactive sort of mode. The buspar, taken prophylactically, is doing very well for me. You MUST work with your doctor to ramp up to the effective dose.

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alwayseek208
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Newly Joined

Registered: June 2007
Location: Mountain Time
Wed July 4, 2007 Recommended? No | Total Spent: None indicated| Rating: 2 

 
PROS: none
CONS: Didn't wake up when my kid needed me to.

I was prescribed this after having sudden 'anxiety attacks' for about a month. I took it for 5 days and really felt as though I was there but not there. Having two very small kids, I couldn't handle not being there for them. On the fifth night, my oldest woke during the night after an 'accident' (still learning) and I had no idea the next morning that my husband had gotten my child up, changed clothes, stripped the bed, and sprayed the mattress pad down outside with the hose. All at 3 in the morning! That scared me, so I stopped the med the next day. Oh, and I still got heart racing and sweats... so it did not really help the nerves to much.

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bopilar51
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Junior Member

Registered: May 2007
Location: Tennessee
Posts: 9
Fri May 11, 2007 Recommended? No | Total Spent: None indicated| Rating: 1 

 
PROS: less than none
CONS: does absolutely nothing. I think it is a placebo

was prescribed twice in a ten year period. first time I didn't notice any change after 6 mo. That was in 85. Was put on Ativan and noticed great positive difference. got taken off ativan by new pdoc who didnt like prescribing benzos. second time last year. now on klonipin. very good

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marshall
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Newly Joined

Registered: April 2007
Sun April 15, 2007 Recommended? No | Total Spent: None indicated| Rating: 1 

 
PROS: does basically nothing
CONS: nothing noticable

I didn't notice any change from this medication.

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lunakit

Newly Joined

Registered: April 2007
Thu April 12, 2007 Recommended? No | Total Spent: None indicated| Rating: 2 

 
PROS: none
CONS: none

No side effects but didn't do anything positive for moods/anxiety either.

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grey

New Member

Registered: March 2007
Location: south of reason, ohio
Posts: 4
Tue March 20, 2007 Recommended? No | Total Spent: None indicated| Rating: 2 

 
PROS: none
CONS: dizziness, weight gain,

It had no effects on my anxiety. I think it actually made me more depressed.

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bipolargirl55
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New Member

Registered: February 2007
Location: Michigan U.S.A.
Posts: 1
Sun February 18, 2007 Recommended? Yes | Total Spent: None indicated| Rating: 9 

 
PROS:
CONS:

I t helps me out alot since I've been on it.

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Thomi

Member

Registered: February 2007
Location: Maine
Posts: 36
Fri February 16, 2007 Recommended? No | Total Spent: None indicated| Rating: 2 

 
PROS: No side effects
CONS: Didn't help anxiety or improve sleep

Was on it to curb anxiety but there was no change after taking it for a few months.

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Direction

Magnate

Registered: December 2006
Location: Midwest, USA
Posts: 2704
Fri January 12, 2007 Recommended? Yes | Total Spent: None indicated| Rating: 7 

 
PROS: It works
CONS: Had a tendency to overshoot (going beyond just being calm almost like too calm) in the first 1/2 hour and drop off and then come back up and then drop off too early

Try it to see if it works for you if not clonzapam might work better

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mama2ak

New Member

Registered: December 2006
Location: Minnesota
Posts: 4
Sat December 30, 2006 Recommended? No | Total Spent: $10.00| Rating: 1 

 
PROS: Price
CONS: Does nothing!

This did absolutely nothing for my anxiety symptoms on 3 different tries. I have a bottle full of it just sitting in my closet. Blah. It's like drinking water... no effect at all.

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Brookester
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Member

Registered: December 2006
Location: California
Posts: 47
Thu December 21, 2006 Recommended? Yes | Total Spent: None indicated| Rating: 1 

 
PROS: NONE
CONS: it doesn't do anything

this is one of the more worthless meds on the market. It virtually does nothing to one's anxiety level.

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Sun September 24, 2006 Recommended? No | Total Spent: None indicated| Rating: 1 

 
PROS: none
CONS: didn't work at all--no effect

Didn't work at all for me for depression or anxiety.

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eskielover

Legendary Wise Elder

Registered: October 2004
Location: Kentucky, USA
Posts: 21835
Thu September 14, 2006 Recommended? No | Total Spent: $20.00| Rating: 5 

 
PROS: no bad side effects
CONS: no effect of anxiety

Buspar was the first medication I was given for my anxiety attacks I started having in 1994. I found that is had no effect on my anxitey level & was like taking nothing. My anxiety level continued to worsen even with the use of buspar.

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DizzyLizzy

Junior Member

Registered: August 2006
Location: New England
Posts: 13
Mon September 11, 2006 Recommended? No | Total Spent: None indicated| Rating: 3 

 
PROS: it did help my generalized anxiety
CONS: lots of side effects, the worst was a constant diziness

Side effects were numerous and constant... and feeling dizzy 24/7 made it impossible to live a normal life.

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alisandria

Veteran Member

Registered: August 2006
Location: USA
Posts: 303
Fri September 8, 2006 Recommended? Yes | Total Spent: None indicated| Rating: 2 

 
PROS: n/a
CONS: felt like I was in a fog, disorientated, agitated.

I didn't care for this medication at all, even after being on it for close to a month, I never seemed to get out of the "cloud" I was in. I felt that side affect was worse than the initial anxiety.

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niko851

Member

Registered: March 2006
Location: Noblesville, IN USA
Posts: 75
Tue July 25, 2006 Recommended? No | Total Spent: None indicated| Rating: 1 

 
PROS: Unknown
CONS: irritability, price, non-fast acting

This med really did nothing for me. After the initial 'waiting' period for it to kick in, nothing ever happened. It seemed as if this medication was a placebo. About the only thing it did for me was make me more irritable.

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