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Cymbalta (duloxotine hydrochloride)

Overall Rating
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2.91
Rating:

2.91

***
(Out of 5 Stars)
Side Effects
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2.44
Pricing
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2.73
Average Price: $53.53 Thumbs up Recommended By
63% of reviewers (of 79 reviews)
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Cymbalta®

Generic Name: Duloxetine hydrochloride

Drug Class: Antidepressant, SSNRI

 

Contents

 

Description
This medicine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). This medicine is used to treat depression. This medicine is also used for nerve pain (peripheral neuropathy) in diabetic patients. Your doctor may prescribe this medicine to treat other conditions.
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General Information
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider. 

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Proper use of this medicine
Follow the directions printed on your prescription label. Ask you doctor or pharmacist if you have any questions about how to take this medicine. This medicine should be taken by mouth. This medicine should be swallowed whole and should not be chewed or crushed, nor should the contents be sprinkled on food or mixed with liquids. All of these might affect the enteric coating. Do not quickly stop this medicine without talking to your doctor.
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Missed Dose
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
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Storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed.
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Possible Side Effects
    • Talk to your doctor if these side effects are bothersome or do not go away:
      • nausea
      • drowsiness
      • dizziness
      • nervousness
      • insomnia
      • headache
      • increased sweating
      • lightheadedness
      • sexual problems
    • A few of the most common side effects with this medicine include:
    • nausea
    • dry mouth
    • constipation
    • fatigue
    • somnolence
    • increased sweating
    • If you experience other bothersome side effects, contact your health care provider.
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Warnings/Precautions
    • Patients and their families should be alert to personality changes such as increased agitation or talk of suicide.
    • Do NOT stop taking this medicine without first talking to your doctor.
    • Alcoholic beverages can increase the effects of this medicine and should be avoided.
    • This medicine may cause drowsiness or dizziness.
    • Before taking this medicine, notify your doctor if you have:
      • history of alcohol abuse
      • narrow-angled glaucoma
      • kidney problems
    • Patient should watch for worsening depression or suicidal tendencies. If you are feeling more agitated, talk to your health care professional.
    • This medicine can cause dizziness or drowsiness.
    • Be cautious when driving or performing other hazardous activities.
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Overdose
Seek medical attention immediately. For non emergencies, contact your local or regional poison control center at 1-800-222-1222.
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Drug Interactions
    • Patients should be advised to inform their physicians if they are taking, or plan to take, any prescription or over-the-counter medications, since there is a potential for interactions.
    • If you are taking a group of medicine called "MAO inhibitors", they cannont be taken with this medicine. Stop the MAO inhibitor 14 days prior to starting this medicine. Your doctor or pharmacist can assist you with this.
    • Before taking any new medications, either prescription or over-the-counter (OTC), talk to your doctor or pharmacist about mixing medicines.
    • Avoid taking St. John's Wort with this medicine.

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Pregnancy/Nursing
Patients should be advised to notify their physician if they become pregnant or intend to become pregnant during therapy. Neonates exposed to SSRIs or SNRIs late in the third trimester have developed complications requiring prolonged hospitalization. (1) Nursing is not recommended while taking this medicine.
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More Information

For more information about this medicine, talk to your healthcare provider.
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Copyright © 2006 PharmClips, Inc. All rights reserved. www.pharmclips.com
This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.



Last reviewed:

  On 8 Aug 2006

  By John M. Grohol, Psy.D.



 

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Reviews
 
gevanhee
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New Member

Registered: September 2015
Location: Canada
Posts: 8
Fri January 18, 2019 Recommended? Yes | Total Spent: $5.00| Rating: 8 

 
PROS: Very helpful for pain.
CONS: Absolutely impossible to get off of. Don’t bother trying.

I tried coming off this medication and gave up due to the side effects. It does help for pain. However I wish I never started this med.

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Open_Book
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Member

Registered: August 2014
Location: Georgia
Posts: 40
Sat December 10, 2016 Recommended? Yes | Total Spent: None indicated| Rating: 6 

 
PROS: Helps with pain also.
CONS: None at this time

Free from VA

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moodswings70
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Member

Registered: November 2016
Location: in a house
Posts: 39
Sat November 19, 2016 Recommended? Yes | Total Spent: None indicated| Rating: 5 

 
PROS:
CONS:

Nine years ago, I tried this medication for about 6 months. It worked initially for me, but then stopped. I didn't have any bad side effects from it. It just did not work for my depression. However, I think if you are trying to find a medication that works, it may be worth at least giving this one try. It may not have worked for me, but it may work for you. It was 9 years ago, so I don't remember the price I paid.

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vishva8kumara
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Member

Registered: October 2016
Location: Katubaedda
Posts: 157
Tue October 4, 2016 Recommended? Yes | Total Spent: $13.25| Rating: 9 

 
PROS: Improved mood and emotions. Helps fight OCD, anxiety and stress related complications.
CONS: Doesn't go well with an occasional cup-a-coffee, nothing else wrong. Worried about the effect on liver.

It is quite expensive, but worth every penny. Once I had an espresso before lunch-time while on this and was feeling so edgy for the rest of the day. Other than that I had no problem adjusting into this from Lexapro. I was tapering off Lexapro for two months with relapse of Anxiety and OCD with mood/emotional disturbance - (doc calls as depression). Before starting this I was also having excruciating cluster headaches that later we found out to be stress related. But with this medication, the headaches was very less and short. I was paced in in a period of three days and it started working from the week after. My mood and emotions are more positive. It is as good as Lexapro plus no side effects when adjusting to a new medicine. With Lexapro, I had Orthostatic hypertension and hot flashes whenever upping the dose, but nothing like that with this medication.

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Guener
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Newly Joined

Registered: July 2016
Location: New Mexico
Posts: 5
Mon July 18, 2016 Recommended? Yes | Total Spent: None indicated| Rating: 7 

 
PROS: Effective for Depression; provides pain relief
CONS: Agitation

This worked well in the beginning for me, but I developed extreme agitated mood and had to stop.

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AngieHobbit
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Newly Joined

Registered: June 2016
Location: Troy
Posts: 1
Fri June 10, 2016 Recommended? Yes | Total Spent: $10.00| Rating: 10 

 
PROS: Decreased Depression, Decreased Anxiety, Decreased Pain
CONS: Nausea

It makes me feel normal! It also helped me discover that I have anxiety. It took it away and I didn't even know I had it. Life without anxiety and constant stress is a breath of fresh air. It also helped me feel more comfortable going into unknown social situations. I am a normal, social human being again.

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lifeispeachy
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New Member

Registered: May 2016
Location: warren
Posts: 1
Fri May 13, 2016 Recommended? Yes | Total Spent: None indicated| Rating: 9 

 
PROS: Takes away my depression
CONS: I have had none

I have had no bad experiences with this drug. I have been taking it for years. So glad they came out with generic.

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iheartjacques
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Magnate

Registered: April 2014
Location: world
Posts: 2162
Mon July 27, 2015 Recommended? Yes | Total Spent: $6.10| Rating: 8 

 
PROS: More energy.
CONS: Brain zaps.

Best one I've been on.

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FlowerChild67

Veteran Member

Registered: December 2013
Location: Portland, Oregon
Posts: 625
Mon March 9, 2015 Recommended? Yes | Total Spent: None indicated| Rating: 2 

 
PROS:
CONS:

gave me massive mania and very bad headache.

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spring2014

Grand Member

Registered: September 2014
Location: somewhere between hell and back over the rainbow
Posts: 834
Sat March 7, 2015 Recommended? Yes | Total Spent: None indicated| Rating: 8 

 
PROS: makes my weight stable and my therapist is happy with the results
CONS: kept me up all night for one night

I just started this medication after I gotten off paxil which it was ineffective for me

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samelaine
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Junior Member

Registered: September 2014
Location: Castaic
Posts: 10
Fri September 19, 2014 Recommended? No | Total Spent: $79.00| Rating: 1 

 
PROS: Energy
CONS: Terrible Side Effects

When I first started Cymbalta I was thrown into a manic episode. I felt like I wanted to tear my skin off, the Cymbalta made me so agitated and irritated. I had a bout of energy I hadn't had in a while and was bouncing off the walls. I even ended up tearing my room piece from piece with a screwdriver because I had to release my feelings somehow. I also became extremely angry and anxious while on the pill.

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Baroness4tea
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Member

Registered: May 2014
Location: Telford
Posts: 62
Wed May 21, 2014 Recommended? Yes | Total Spent: $30.00| Rating: 5 

 
PROS: Stopped ruminations
CONS: Diarrhea

Could not take the side effects

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wildsassysam
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Junior Member

Registered: May 2014
Location: liverpool
Posts: 6
Fri May 2, 2014 Recommended? No | Total Spent: None indicated| Rating: 4 

 
PROS: dont see any
CONS: constant sweats nausea

another one thats in my combination but i cant cope with the constant nausea and sweats, ne1 know of a GOOD deodorant as i cant find one to work

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bluekoi

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Registered: February 2014
Location: Vancouver, BC Canada
Posts: 13600
Sun February 23, 2014 Recommended? Yes | Total Spent: $300.00| Rating: 10 

 
PROS: once a day
CONS: price

positive

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bluekoi

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Community Support Team


Registered: February 2014
Location: Vancouver, BC Canada
Posts: 13600
Sun February 23, 2014 Recommended? Yes | Total Spent: $300.00| Rating: 10 

 
PROS: No side effects. Works well for my depression symptions.
CONS: none

Works the best of any anti-depression medicine I have tried. Cons very expensive.

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wolfclaw
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New Member

Registered: January 2014
Location: Kentucky
Posts: 6
Tue January 28, 2014 Recommended? Yes | Total Spent: None indicated| Rating: 8 

 
PROS:
CONS:

Sweaty and helps with focus

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walkerlady

Member

Registered: December 2012
Location: Central Wisconsin
Posts: 49
Wed January 22, 2014 Recommended? No | Total Spent: $125.00| Rating: 1 

 
PROS: none
CONS: price, side effects

this med is very expensive, even though it has come out in generic, no one else is making it so price has not come down. TERRIBLE side effects: Extreme dry mouth, ringing in my ears, went off cold turkey because I couldn't afford it and had hallucinations, rage and suicide attempt

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rainboots87

Veteran Member

Registered: March 2012
Location: usa
Posts: 654
Thu May 2, 2013 Recommended? No | Total Spent: None indicated| Rating: 3 

 
PROS: helped anxiety and depression
CONS: insomnia

I tried this after trying several SSRI's that gave me insomnia, but it turns out Cymbalta gives me insomnia too. It helped a decent amount, but I just couldn't deal with not sleeping well for so many months. Going off the drug was a nightmare though! I was getting hot flashes (I'm only in my 20's) and was just a mess.

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Thu May 2, 2013 Recommended? No | Total Spent: $10.00| Rating: 1 

 
PROS: ------
CONS: short term memory loss

Short term memory loss is bad...happened within a few days of starting it.

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ellipsisdream

Veteran Member

Registered: November 2011
Posts: 355
Thu May 2, 2013 Recommended? Yes | Total Spent: None indicated| Rating: 9 

 
PROS: Depression lifted within weeks
CONS: Nausea first couple of months and bouts of diarrhea

This is the first anti-depressant that has truly worked for me. All of my loved ones have seen the difference, and combined with a low dose of abilify, I am in good space most of the time. I did not know I could feel good without being manic (I am bipolar). I would recommend to others to give this medication a try if they are still struggling on a different med. It has been life changing for me.

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Griffinandsabine
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New Member

Registered: August 2012
Posts: 1
Wed August 29, 2012 Recommended? No | Total Spent: $140.00| Rating: 1 

 
PROS: No emotional ups and downs
CONS: Weight gain, lethargy, migraines, disconnected

This medication should not be prescribed due to the variances of effect between users. I have heard of some experiencing relief, but the vast majority, myself included, have had many negative and harmful side effects, especially during withdrawal. I have been taking Cymbalta (60mg) for two years in conjunction with Wellbutrin (450mg). The problem with taking the medication as a "booster" to other antidepressants is that you then can't determine which medication are causing side effects and what is "normal reality" for someone with depression or other mood disorders. For the past two years I haven't worked, can barely take care of myself and my child, I have gained a significant amount of weight, have no energy for even routine tasks like showering. Is this just what happens when one is depressed? Well, yes and no to a degree. The Cymbalta worked to numb every thought and feeling I was experiencing. I just didn't give a crap about anything and would just sleep as many as 16 hours a day. I also have had daily migraines and stomach cramps while on the medication. I have tried to wean myself off of Cymbalta twice. The first time was accidental because I ran out of medication and couldn't afford more. That time I experienced severe and debilitating withdrawal effects like brain zaps, vertigo, nausea, dizziness, headaches, body aches. It disappeared as soon as I was able to purchase my prescription and start back on the 60mg dose. I am currently weaning myself off again after another year of uninterrupted medication. Four months ago I began taking 50mg, then one month of 30, two months of 20mg and I have not taken anything in 3 days. Yep, all the same side effects are there despite the gradual tapering. On the plus side, for the first time in two years I actually felt energetic. I cleaned my entire house, showered, and then decided to go out amongst the living for a few hours. This is getting closer to how I felt before the deep depression took over my life. I am actually looking forward to getting over the withdrawal hump and feeling normal again. I can't wait to get my libido back and to start feeling emotions again. If Cymbalta was supposed to help, it didn't for me. It made everything much, much worse and if it hadn't been for the scary withdrawal effects that I had experienced the first time I would have stopped taking this drug a long, long time ago. I have lost two years of my life while on Cymbalta. My suggestion is that if your doctor is considering putting you on Cymbalta ask if he/she has taken it. If they haven't, then don't do it. I don't think doctors would be prescribing this medication for anyone if they knew how horrible it makes a person feel. There is something fundamentally wrong with a medication that is supposed to help life a person out of depression and instead pushes them deeper into the abyss. Do they do this so that we are forced to stay on the medicine and therefore continue to buy it, thereby increasing their sales? It seems very unethical to me. People struggling with depression should not be used as guinea pigs. We are already too vulnerable.

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Galymia

Member

Registered: April 2012
Location: b-e-d
Posts: 33
Sun April 1, 2012 Recommended? No | Total Spent: $60.00| Rating: 1 

 
PROS: None.
CONS: Extreme suicidal tendencies.

I was extremely suicidal and out of control on this medication. It also made me very constipated, which added to the horrible mood I was in while I was on this. The price was horrible, even with insurance. Stay away from this one.

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glowinlk
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New Member

Registered: December 2011
Posts: 1
Sun December 18, 2011 Recommended? Yes | Total Spent: $3.00| Rating: 10 

 
PROS: Depression RELIEVED
CONS: Mild Stomach Upset/Burning

Give it a good try; use Tums or omeprazole for stomach side effects; don't miss a dose; I found taking it at noon works best for me; keep hydrated; combine with psychotherapy. I have been depressed for decades. I am also a recovering alcoholic/drug addict (clean/sober for five years now). I suffered from major depressive disorder, suicidal ideation and attempts, seasonal affective disorder, generalized anxiety, self mutilation, and dysthimia (sp?). I tried paxil, welbutrin, lexepro, and celexa. Cymbalta has finally relieved my depression. I have been on Cymbalta for nine months. I am curious to see how I do this winter - depression is usually worse for me in winter months; this will be my first winter on Cymbalta. I attend psychotherapy and also tend to my spiritual health. The horror stories of Cymbalta kept me away from it. Out of desperation I tried it finally; so glad I did! If and when I come off of it, I will treat it as a med that needs progressive withdrawal measures. I recently started taking clonazepam for anxiety. The combination is working well for me. I take 1/2 tab of clonazepam at night I take 60 mg of Cymbalta at noon. I get flu like symptoms (body aches/fatigue) immediately if I skip a dose or am late with a dose. I get occasional stomach upset/burning, which I take Tums and omeprazole to relieve. No other side effects thus far. For me, suicidal ideation was immediately relieved within first couple weeks of taking Cymbalta. (Life is so much easier without those pesky, self loathing, negative thoughts!) Cymbalta also lessens menstrual cramps and lower back pain for me; although, I still take NSAIDS for both occasionally (even though the use of NSAIDS and Cymbalta is cautioned). I am very pleased with Cymbalta's treatment of depression!

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Remmy2011
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New Member

Registered: November 2011
Posts: 1
Tue November 1, 2011 Recommended? No | Total Spent: None indicated| Rating: 4 

 
PROS:
CONS: dizziness, headbuzz

aside from the dizzy feeling, i really didnt like the headbuzz or headshocks as it appears to be called. i also had a very hard time reaching climax while on this medication (took it for about 5 months). does anyone know what exactly in cymbalta causes this?? i felt that as a whole cymbalta wasn't too bad compaired to some of the other medications i've tried in the past .. but this inability to reach climax is what eventually pretty much started to cause counter active thoughts. i have tried looking all over for what specific element in this medication causes it, but have never found an answer .. puzzling.

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o.kay
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Member

Registered: October 2009
Location: USA
Posts: 78
Sun October 16, 2011 Recommended? Yes | Total Spent: $50.00| Rating: 8 

 
PROS: Does help reduce depressive feelings
CONS: sexual issues, cost & fatigue

it helps but I also take this with other antidepressents

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ost324
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Junior Member

Registered: February 2011
Location: US
Posts: 7
Mon October 10, 2011 Recommended? Yes | Total Spent: $100.00| Rating: 8 

 
PROS: effective quickly
CONS: wears out fast

Worked very well for depression, felt relief very quickly with limited but strange side effects, like pupil dilation. Pooped out after about 4 months for me, and the withdrawal symptoms are terrible, plus my insurance didn't want to pay for it, which was unfortunate because overall it was the best anti-depressant I've tried yet!

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dbro
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New Member

Registered: March 2011
Posts: 2
Fri March 4, 2011 Recommended? Yes | Total Spent: None indicated| Rating: 10 

 
PROS: more energy, reversed my depression and anxiety,
CONS: none yet

I was suffering from a long episode of major depressive disorder, insomnia, anxiety and panic attacks. Oh and throw in chronic pain, lots of injuries and surgeries from years of sports. I made several half hearted attempts at suicide then found a way to fully commit to it. By a miracle I was found just as I stopped breathing. I am on about 4 months 60 mg 2x a day. No suicidal thoughts even though I am unemployed, homeless and trying to support my family. I actually am now clear headed and moving forward. It took me about 4 months to get to this point plus I went to therapy. I used to have daily headaches and frequent migraines but they stopped completely since being on this. I was on Xanax 2mg 3x a day but realized I didn't need it anymore. I stupidly went cold turkey on the xanax and ended up having mild to moderate lower grade seizures for a week. I briefly went back on xanax to do a rapid ween with neurontin. The schedule was 4 weeks I did it in two. I haven't noticed any cymbalta side effects. I did put on 30 pounds in a month but I am exercising and already took 17 off. Good luck to all.

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ost324
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Junior Member

Registered: February 2011
Location: US
Posts: 7
Mon February 21, 2011 Recommended? Yes | Total Spent: $100.00| Rating: 4 

 
PROS: Helped a lot at first with depression, loss of appetite at first!
CONS: Loses effectiveness after only a couple months, weird body ticks, increased anxiety, extra sleepy

It helped me a lot at first with very few negative side effects, very mild loss of appetite at worst. But after a couple of weeks I developed some weird ticks like kicking my foot in class and while in bed, something I've never done before but couldn't stop! After a couple of months, it's unfortunately completely stopped working for me at the max dose, and I also suspect it makes me even more sleepy than usual. I'm currently still taking it anyway, but I hear the withdrawal effects are terrible too. Yay.

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somethingintheway13
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Newly Joined

Registered: December 2008
Sun June 13, 2010 Recommended? No | Total Spent: None indicated| Rating: 5 

 
PROS: helps depression at low doses
CONS: increased anxiety, increased sweating, increased thought of food, suicidal thoughts

Ive been on this med for 5 months. It worked quickly and made me less depressed. But as my depression went down, my anxiety went up. I strted sweating perfusly at anything that made me in the least anxious. It made me thin more of food(i am a bulimic/anorexic) and as i increased my dose it made me more and more suicidal

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thetruthdoctor
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Newly Joined

Registered: April 2010
Fri April 30, 2010 Recommended? No | Total Spent: None indicated| Rating: 1 

 
PROS: Slightly lessened the neuopathy pain in my feet and legs
CONS: I swear to everything that is holy that this drug (Cymbalta) should be immediately taken off the market!

I pray that if you are considering taking this medication you read this first. 1, This medication is a lifetime commitment. 2. If you choose to stop taking Cymbalta be ready for the most God-Awful mind destroying hellious experience of your life....that is if you are strong enough to beat the devil! This drug manufacturer has no idea (or maybe they do...and don't care)about the withdrawl problems with this drug. I am very lucky to survive the constant "brain Zaps" that almost killed me. I took loads of Benedryl to help with the constant electronic nerve "shocks" That I suffered for 2 months!! I swear to everything that's Holy....DO NOT TAKE THIS MEDICATION!!!!!!

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kaybadkins
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Newly Joined

Registered: March 2010
Sat March 20, 2010 Recommended? Yes | Total Spent: $50.00| Rating: 10 

 
PROS: Drug controls moods very well.
CONS: Cannot just stop taking the drug - will have withdrawal symptoms.

I love this medication and it has really made a difference in my life. My doctor tried to take me off of it and had to put me right back on it.

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psychodwnldr
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Newly Joined

Registered: October 2009
Location: maryland
Sat October 17, 2009 Recommended? Yes | Total Spent: None indicated| Rating: 10 

 
PROS: controlls my anger & moodswings
CONS: none that i can tell

my doctor put me on cymbalta back in augest of this year for my anger and mood swings. best thing thats happened. my wife & childern noticed a major difference in my behavior the 1st day i was one it. i've been diagnosed w/cyclothymic personality disorder i started out on 30mg then bumped to 60mg now i take 120mg. from 1st day i started i've been full of energy,maybe a little too much.3am i'm still wide awake wanting to do thing around the house.if im lucky i get 4 hrs sleep but still bursting w/energy next day.it works for me

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CRW60088
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Newly Joined

Registered: September 2009
Wed September 2, 2009 Recommended? No | Total Spent: None indicated| Rating: 4 

 
PROS: thoughts were clearer
CONS: major side effects

I first had trouble sleeping, so my dose was lowered until I got use to it. Then I had abdominal pain, and tar like stools. Very painful to pass. I had a colonscopy and an endoscopy. I'm 32. It wasn't pleasant. After these were cleared, I started having sharp pains in one breast, then I started to leak. I thought it was puss, but later found out it was milk. I have never been pregnant, I found it quite scary, and the doctors thought I had breast cancer. Got tested, no cancer~!!! yeah!! Got off Cymbalta and all the symptoms went away. The doctor's never looked at these issues as side effects even though it was my only new prescription. My doctor said the medication was tested on men, so leakage wasn't a issue.

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Richardinvegas
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Newly Joined

Registered: March 2009
Fri March 20, 2009 Recommended? Yes | Total Spent: $50.00| Rating: 9 

 
PROS: Stablized my moods
CONS: None, yet

I have been on cymbalta (after Effexor XP) for over a year and it is, so far, my miracle drug. I don't get my highs and lows in depression/anxiety and I am lucky not to have any side effects that I have noticed. I am much happier in life on it. One exception...I am still havind difficulty coping with people...they just don't get me!!?? I try to be liked, but I constantly fail. Thanks you Cymbalta

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lavitsef
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Newly Joined

Registered: March 2009
Sun March 8, 2009 Recommended? Yes | Total Spent: $20.00| Rating: 9 

 
PROS: it works and relieved leg cramps
CONS: occasional mild dizzy

Went from Prozac forever to Cymbalta. I had leg cramping and tight leg muscles. Cymbalta 60 mg stopped the leg tightness and works well for mild depression. Good product

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Taonuviel

Poohbah

Registered: May 2004
Location: Michigan
Posts: 1455
Fri August 22, 2008 Recommended? No | Total Spent: None indicated| Rating: 1 

 
PROS: None
CONS: Withdrawal is Hell. Dangerous. Often leaves you with a strange feeling of illness/weakness.

This stuff's so bad, I hope some lawsuit will come out against Lilly so I can join. Evil greedy poisonous monsters... Find out for yourself, search "Cymbalta withdrawal".

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retrobaby

Newly Joined

Registered: July 2008
Thu July 31, 2008 Recommended? Yes | Total Spent: $15.00| Rating: 4 

 
PROS: Hmmm, not crying
CONS: sweat like a pig!! can't sleep at night (2:30a.m., here I am), constipaaaation.

I've been on this since it became available at various doses. Doc switched from Wellbutrin/Lexapro to Cymbalta simply in the hope it would aid in pain relief & help depression(remained on Lexapro). I don't know ..... I miss my Wellbutrin. At 120mg I ended up in the ER w/tachycardia. Weaned off Lexapro, then down to 30mg on Cymbalta, couldn't stop crying, again-miss my Wellbutrin.... but I could poo! On 60mg now for a couple months, think I've hit a wall, can't sleep even tho Lyrica makes me weary .... better suck down my Ambien. Is there a maybe recommendation?

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trillian
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Newly Joined

Registered: July 2008
Tue July 22, 2008 Recommended? Yes | Total Spent: None indicated| Rating: 0 

 
PROS: made me happy
CONS: made me manic, night sweats, brought back addictions, bad withdrawals even if weening off, don't care about anything

well, seemed alright at first, but got to the point i was tired i went home and read all afternoon until bed. but when i went to bed, couldn't sleep. i didn't care about doing housework, my performance at my job suffered cause i just didn't care and didn't fell like doing anything. as with prozac, i picked up my old addictions that i have been clean from for almost three years. all in all, i lost $5,000 to my addictions while the doctor tried to find the right anti-depressant. i went from functional but moody and agitated to not-functional. i'm done trying, my family, my checkbook, my life can not go through "trying" another anti-depressant. even if you ween off it, the withdrawals are awful, joint pain, headaches, nausea, constant crying.

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runnergrrl
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New Member

Registered: January 2008
Posts: 1
Mon July 21, 2008 Recommended? No | Total Spent: $35.00| Rating: 3 

 
PROS: decreased depression and suicidal thoughts
CONS: Problems urinating at night, headaches, tiredness, dry mouth

Started taking Cymbalta in June of '08. Got up to 60 mgs. Felt great at first but, have side effects from it. Biggest problem is getting up several times a night to urinate, but can't do it. Starts around 4 am and does not stop until I get up for the day. Extreme tiredness due to this problem. Dry mouth is a problem too. Overall, this drug is ok. But, dreading hearing about the withdrawal symptoms after experiencing them with Effexor. I cut cold turkey at 60 mgs only being on the drug for less than a month. -------- Day 3 of withdrawal from Cymbalta. Mind you I was only on this drug for 24 days. I have been through the Effexor (after being on it for almost 2 years at 150mg) withdrawal and thought that this withdrawal would be a picnic. I can't believe how terrible the past 3 days have been. I have been extremely dizzy, brain zaps, cold sweats, and peeing all the time (I think this is due to the fact that I had urinary problems with Cymbalta and now that it is getting out of my system, I am able to urinate again - kinda scary knowing this). I hope that day 4 proves to be like it was when I was going through with the Effexor withdrawal. I started to feel better then. But, who knows. Cymbalta doesn't mess around. ------- Day 6 of withdrawal from Cymbalta. Feel much better, though still have weird brain zaps and a little bit of vertigo. But, I started to drink green tea and have been drinking lots of fluids the past few days. I definitely feel much better today than six days ago. I was lucky I did not have work and could lay in a dark room with the air conditioning on for a week. *It will be different for a lot of people due to various reasons like dosage amount, length of time on medication... I got off of Effexor in six days, so my metabolism must be faster than others.

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Is4110

New Member

Registered: May 2008
Location: SW Arkansas
Posts: 5
Fri July 18, 2008 Recommended? No | Total Spent: None indicated| Rating: 4 

 
PROS: Relieved depression.
CONS: Side effects.

I only took it once and it totally spaced me out. Plus, I couldn't urinate! No joke..when I went to the toilet, I would sit there for 2-3 minutes waiting for the message from my brain to reach my bladder to release the urine. I'm not kidding. It was like I had no control over my bodily function! Glad I didn't stay on it!!

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trillian
avatar of person

Newly Joined

Registered: July 2008
Fri July 11, 2008 Recommended? Yes | Total Spent: None indicated| Rating: 7 

 
PROS: i feel much better
CONS: dry mouth, night sweats, pounding heart, aggitated feeling, makes my skin crawl

well i am still taking it. haven't been on it long. hoping some side effects go away but the ones i have are bareable compared to the prozac manic episode that cost me 3,000 dollars. trying tranzene to counter-act the agitation.

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jen29

Grand Member

Registered: June 2008
Location: Wisconsin
Posts: 841
Tue July 1, 2008 Recommended? Yes | Total Spent: None indicated| Rating: 8 

 
PROS: Extremly helpful with depression
CONS: Only FDA approved for 60 mg, so Insurance won't cover it with I need a boost.

I have been taking cymbalta since it first came out, about 2 or 3 years. It works great when I take it. If I miss just one dose I get the worst headache. It does go away about 4 hours after I take it again. My doc. wants to put my one 120 mg, but having problem with ins. co.

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MyCatPete
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New Member

Registered: June 2008
Posts: 2
Wed June 25, 2008 Recommended? Yes | Total Spent: $0.70| Rating: 9 

 
PROS: Less anxiety, better sleep
CONS: Side effects hard to overcome at first

I started out on 30mg to help with depression/anxiety. The side effects were very hard to overcome at first - I was extremely tired, constantly yawning, sweating easily, and experienced nausea. My doctor increased my dosage to 60mg after one month. My side effects also increased, but I also noticed many positive results. I haven't had a panic attack in several months, my depression has eased, and my appetite is back to normal. I have been taking Cymbalta for 7 months and am so far pleased with the results.

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emi24
avatar of person

Newly Joined

Registered: June 2008
Sun June 22, 2008 Recommended? Yes | Total Spent: None indicated| Rating: 8 

 
PROS: helped with anxiety and TMJ problems
CONS: slight nausea and insomnia for the first week or so but not too bad

i was such an i-don't-believe-in-western-medicine-especially-anti-depressants type person but i tried cymbalta after my doc highly recommended it. i was hesitant but tried it as a last resort as i am dealing with chronic neck pain, TMJ, and fatigue which was causing severe depression and anxiety. i had even tried effexor for 6 weeks before which is a similar drug but experienced several side effects. cymbalta has not banished my physical ailments but has allowed me to focus on other things and not so much on the pain. i was in so much pain i could not even function. now, i am able to. the pain is still there but the anxiety about the pain is gone as well as the major depression. i feel like it just gives me better coping skills or something. i'm not saying its a permanent fix but until i get whatever it is going on resolved, cymblata helps me deal with it in the meantime. i have no side effects yet and it has been 4 weeks. i started to feel better after only 6 days which is faster than most SSRIs and SNRIs. i just wanted to give cymbalta a fighting chance because there are so many negative things said about it. it may not be for you because its different for everyone but i'm telling you...for the time being it has saved my life. give it a chance!

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OMGthathurts
avatar of person

Newly Joined

Registered: June 2008
Location: Tulsa, Oklahoma
Sun June 15, 2008 Recommended? No | Total Spent: None indicated| Rating: 6 

 
PROS: I felt better than I had in years, really seemed to do the trick
CONS: sweating

I felt better than I had in years, and it helped plantar fasciitis, urinary incontinence as well as my depression. I had so many hot flashes, my scrubs were soaked, and my face was red all the time. Eventually it stopped working on the depression. Now in weaning off, I'm having strange electrical type shocks in my brain and body, I am crying a lot and had about a week of nausea. This is much worse than the depression itself, and when I tried to go back on full strength again, it didn't work. I am miserable. Trying to take Welbutrin now, I already take clonazapam for night terrors.

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katfriendly

Junior Member

Registered: April 2008
Location: OHIO
Posts: 6
Sun April 27, 2008 Recommended? Yes | Total Spent: None indicated| Rating: 10 

 
PROS: This has kept my deep depressions to a minimum.
CONS: When I first started on Cymbalta, had minor accidents (bathroom, i mean).

This antidepressant has worked better for me than any other, and believe me, I think that I have tried most of them.

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_Hope_

Grand Poohbah

Registered: September 2007
Location: MA
Posts: 1807
Mon April 7, 2008 Recommended? Yes | Total Spent: None indicated| Rating: 3 

 
PROS: none yet
CONS: sexual problems , dehydration, constipation

I have only been on it 2 weeks , I havenot noticied anything good yet , but the worst is an inability to orgasm, that doesn't help my depression much

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TaintedGoth1

Grand Member

Registered: April 2008
Location: PA, USA
Posts: 959
Sun April 6, 2008 Recommended? Yes | Total Spent: None indicated| Rating: 8 

 
PROS: Excellent for depression
CONS: Wears off too soon

I really would recommend this. I've not had the side effects noted by others and do extremely well on this medication. Take it midday as sometimes it does not have the same potency in the evening if you take it in the morning.

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mazer

Member

Registered: January 2008
Location: in my own crazy world
Posts: 20
Sun April 6, 2008 Recommended? No | Total Spent: None indicated| Rating: 0 

 
PROS: none
CONS: makes you feel shit

should be banned as its awful to come off,been on it for over 2 years and cant get off this poison !

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Anonymous
Mon March 17, 2008 Recommended? Yes | Total Spent: None indicated| Rating: 5 

 
PROS: decreased appetite
CONS: fatigue, feeling a bit "foggy"

I've only been taking this for four days, but so far I don't have any complaints. I'll probably be posting in a week or two with an update. I listed the decreased appetite as a "pro", because I'm 50 pounds overweight, so I'm not complaining about that.

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