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Default Jun 22, 2018 at 02:22 PM
  #1
How do those extended release (XR) capsules work? The ones with the little beads in them.
Adderall XR, Effexor XR. Those are the two I can think of.

Thanks. Just very curious.

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Default Jun 22, 2018 at 02:35 PM
  #2
They release a consistent am out of medication over time so hopefully you only need it once a day instead of two or three.

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Default Jun 22, 2018 at 02:41 PM
  #3
Interesting question. Not all capsules are XR which I find interesting too.
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Default Jun 22, 2018 at 05:38 PM
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Originally Posted by 88Butterfly88 View Post
Interesting question. Not all capsules are XR which I find interesting too.
I think it depends on the drug in question & whether it can be manufactured in such a way as to safely be digested at a controlled dose over x period of time, whilst minimizing any risk of accidental overdose due to it being absorbed in the system too quickly (like some drugs when grapefruit has been consumed).

I've a (possibly cynical) feeling that XR ia also used as a technique to extend patent rights when the regular product is going to become available for generic manufacturers.

BTW, those beads are designed to dissolve in the stomach at different rates, giving the extended dosage release.
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Default Jun 22, 2018 at 07:08 PM
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Funny story..sort of I am on 600 mg of Effexor xr. I had a colonoscopy done and they found those little beads all over my colon. Now I have to go for a colonoscopy every 5 years instead of 10.....
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Default Jun 22, 2018 at 08:40 PM
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Funny story..sort of I am on 600 mg of Effexor xr. I had a colonoscopy done and they found those little beads all over my colon. Now I have to go for a colonoscopy every 5 years instead of 10.....
Wow, what a whopping dose of Effexor Dr. My pdoc told me 300mg was the highest he would go, that 300 mg was the highest safe dose. I can see why the doc saw all those little beads!

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Default Jun 23, 2018 at 10:53 AM
  #7
Thanks all.

I think I read somewhere that they are little polymer beads.

Y I K E S! I might ask my doc about that beads in the colon thing. Wow.

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Default Jun 23, 2018 at 06:42 PM
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Originally Posted by Bird Feeder View Post
Funny story..sort of I am on 600 mg of Effexor xr. I had a colonoscopy done and they found those little beads all over my colon. Now I have to go for a colonoscopy every 5 years instead of 10.....
600 mg, wow. 75 mg caused me to have a rapid heartbeat and they decided to take me off it completely.
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Default Jun 24, 2018 at 10:13 AM
  #9
I have been on the 600 mg dose for the past 20 years. When I had to switch pdocs after 15 years he kept me on the dose because I seem to tolerate it well...which I do. I do know it is a large dose:-) but it works for me.

I also take:
Clozaril 75 mg
Welbutrin. 450 mg
Abilify 15 mg
Klonopin 1mg
Synthyroid 150 mcg.

I still function well and hold down a full-time job. I'm a lucky person.
But watch those colonoscopies:-))).
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Default Jun 24, 2018 at 11:59 AM
  #10
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Originally Posted by Bird Feeder View Post
I have been on the 600 mg dose for the past 20 years. When I had to switch pdocs after 15 years he kept me on the dose because I seem to tolerate it well...which I do. I do know it is a large dose:-) but it works for me.

I also take:
Clozaril 75 mg
Welbutrin. 450 mg
Abilify 15 mg
Klonopin 1mg
Synthyroid 150 mcg.

I still function well and hold down a full-time job. I'm a lucky person.
But watch those colonoscopies:-))).
I guess you must have been on the RRXR (Really, Really eXtended Release form - still, thanks for getting us to the bottom of this.
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Default Jun 25, 2018 at 06:22 AM
  #11
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Originally Posted by marvin_pa View Post
I guess you must have been on the RRXR (Really, Really eXtended Release form - still, thanks for getting us to the bottom of this.
Funny!
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