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Old 09-04-2018, 06:43 PM #31
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Default Re: AP Switching: Aripiprozole to Quetiapine

sometimes, a stimulant (upper) plus a tranquilizer/neuroleptic is a good option. I have an acquaintance (not with your son's set of problems, but...still...) who found relief from a broad range of "issues" with seroquel at night and an adderall xr capsule in the morning. the downside is I think there's some indication the TD risk goes up a bit, and if one gets problems from the neuroleptic (akathisia comes to mind), then the amphetamine or Ritalin can make it worse, not better. blah.

sorry about this situation.
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Old 09-04-2018, 07:34 PM #32
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Default Re: AP Switching: Aripiprozole to Quetiapine

For the very brief period of time I took Seroquel it totally wiped out any effect of stimulants. I think it has to do with how fast your body processes the neuroleptic. For some it goes faster.

The good thing with stimulants is that they don't need to be taken on a daily basis to work, one can take them when needed the most and then take breaks from them. Which is probably when they work the best.
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Old 09-04-2018, 10:22 PM #33
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Default Re: AP Switching: Aripiprozole to Quetiapine

dosing is an issue, too. it seems that neuroleptics=higher upper dosage to achieve whatever effects are being sought in treatment. Having said that...

for a while there, shrinks relied on "goof balls"--they were combo pills, part upper and part either sedative (usually a barbiturate) or carefully dosed neuroleptic. The ones w/ the upper and the neuroleptic were effective for weight loss, some forms of depression, etc., but there were also occasional horror stories (TD, addiction, etc.). Anyway...

some things never change. Now, it seems to be an amphetamine for "ADD" and then Klonopin for "anxiety." basically the same thing, just...2 prescriptions to fill, 2 diagnoses to contend with, etc. The Ultimate Goof Ball is a downer, a neuroleptic, and an upper. Not the best idea over the long haul, but...effective for extreme states of misery, no doubt.
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Old 09-05-2018, 02:00 PM #34
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Default Re: AP Switching: Aripiprozole to Quetiapine

Quote:
Originally Posted by -jimi- View Post
... made me feel like I was even way closer to the world, and everything was hyper real. Like every impression, every thought, really got to me. Like I had no protection from anything. The world mentally scorched me.

...

My anger stemmed from everything being too close and getting to me. It is kind of hard to explain. I couldn't drop negative emotion, it just built up.

...
Exactly. That's exactly how our son has described it and we've seen how negative emotion builds up and once it gets going he focuses on it to the exclusion of everything else. He cannot be consoled.


Actually, the idea of 'focusing on (idea, thing, person, food, want) exclusively, completely out of perspective is a life-long trait. With the advent of adult-sized rage replacing the irritability of his childhood, we see him likewise fixating on that.


As far as benzos are concerned, him being 16, they aren't going to give those to him, even if it helped.
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Old 09-05-2018, 02:26 PM #35
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Default Re: AP Switching: Aripiprozole to Quetiapine

Quote:
Originally Posted by still_crazy View Post
sometimes, a stimulant (upper) plus a tranquilizer/neuroleptic is a good option. I have an acquaintance (not with your son's set of problems, but...still...) who found relief from a broad range of "issues" with seroquel at night and an adderall xr capsule in the morning. the downside is I think there's some indication the TD risk goes up a bit, and if one gets problems from the neuroleptic (akathisia comes to mind), then the amphetamine or Ritalin can make it worse, not better. blah.

sorry about this situation.
Quote:
Originally Posted by -jimi- View Post
For the very brief period of time I took Seroquel it totally wiped out any effect of stimulants. I think it has to do with how fast your body processes the neuroleptic. For some it goes faster.

The good thing with stimulants is that they don't need to be taken on a daily basis to work, one can take them when needed the most and then take breaks from them. Which is probably when they work the best.
Quote:
Originally Posted by still_crazy View Post
dosing is an issue, too. it seems that neuroleptics=higher upper dosage to achieve whatever effects are being sought in treatment. Having said that...

for a while there, shrinks relied on "goof balls"--they were combo pills, part upper and part either sedative (usually a barbiturate) or carefully dosed neuroleptic. The ones w/ the upper and the neuroleptic were effective for weight loss, some forms of depression, etc., but there were also occasional horror stories (TD, addiction, etc.). Anyway...

some things never change. Now, it seems to be an amphetamine for "ADD" and then Klonopin for "anxiety." basically the same thing, just...2 prescriptions to fill, 2 diagnoses to contend with, etc. The Ultimate Goof Ball is a downer, a neuroleptic, and an upper. Not the best idea over the long haul, but...effective for extreme states of misery, no doubt.

Ja, the amp salts seem to have the most straightforward, WYSIWYG effect. In, does what it does and then out. They did seem to help with his unbelievably short attention to work but could also ignite his mania/perseverance and up the irritation (as if it weren't already in the red) in the later part of the day, not to mention the tics, which, even when the offending med is dropped, often continue on their own.



Odd thing was the stims seemed to make him far more compliant when they are first working, otherwise his personality is naturally hyper objectionist, hyper oppositionist.


As it turns, the matter is now out of our hands. He had to be admitted yesterday - something that has never happened before.


They're in the process of drawing up medication changes and will submit the to us in the near term. I'm wondering if they will come back with some sort of "goof-ball" combo, as you mentioned. I wouldn't be surprised.


Just hope they can find the right mix.


Thanks to all of you for your responses.
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Old 09-05-2018, 06:35 PM #36
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Default Re: AP Switching: Aripiprozole to Quetiapine

I hope things will be better from now on.
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Old 09-08-2018, 09:36 AM #37
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Default Re: AP Switching: Aripiprozole to Quetiapine

Hope he will get well soon.

I'm also switching from Risperidone to Seroquel from tonight and nervous about that.
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Old 09-08-2018, 06:20 PM #38
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Default Re: AP Switching: Aripiprozole to Quetiapine

Quote:
Originally Posted by vishva8kumara View Post
Hope he will get well soon.

I'm also switching from Risperidone to Seroquel from tonight and nervous about that.

Thank you kindly for the well wishes, Vishva.


You're switching from Rispiridone to Seroquel or from Seroquel to Rispiridone?


Cheers,
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Child-like - no one understands
Jack knife - in your sweaty hands
Some kind of innocence is measured out in years
You don't know what it's like to listen to your fears


Big man - walking in the park
Wigwam - frightened of the dark
Some kind of solitude is measured out in you
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Old 09-10-2018, 09:53 AM #39
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Default Re: AP Switching: Aripiprozole to Quetiapine

I've been taking Lexapro and Risperidone. It is now the third day I'm titrating into Seroquel. Still at 50mg. Tomorrow I have to take the 100mg. Lexapro dose is unchanged.

I'm wondering how long it will take for Seroquel to start working. I already feel a little bit of relief, it is hard to explain it.
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Old 09-10-2018, 09:54 AM #40
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Default Re: AP Switching: Aripiprozole to Quetiapine

from Rispiridone to Seroquel
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