Anyone gain weight on Gabapentin?

I'm not yet sure if I've been gaining weight, but hubby made a comment today. Wasn't mean. And he said it could have just been the shirt or bloat even. But now we are concerned it might be the new med I'm taking. I've Googled and have seen varying opinions/experiences on this. Just curious what folks here have experienced. Thanks!

I t was weight-neutral for me for many years.

Yes, for some, it will eat you out of house and home. Speaking from experience, as soon as a took a bite of food. Well, I was like Man vs Food = not good I never felt satiated . It is actually used of label for people that have anorexia issues. I have talked to my pdoc about this as I have used the med. of and on but the issue of gaining weight is to strong. For those who have never used it. Gabapentin is a great anxiety drug but it can make many people gain weight. There are studies on pubmed about the issue. Also , I think it is dose dependent imo and can be regulated by certain supplements and also when you take the medication. Even if I took it at night there was a carry over for the next two days in my anecdotal experience. Obviously the dose and the time, play into the half life uhhhh. Pregabalin: A Review of its Use in Adults with Generalized Anxiety Disorder | SpringerLink Actually this is what I was looking for to dig deeper into the issue: Pregabalin increases food intake through dopaminergic systems in the hypothalamus - ScienceDirect" Pregabalin significantly increased food intake, whereas pregabalin did not affect blood glucose levels. These results indicate that pregabalin stimulates feeding behavior, but not glucose metabolism. Moreover, the non-selective dopamine receptor antagonist cis-(Z)-flupenthixol injected into the LH significantly increased food intake, though neither the dopamine D1 receptor antagonist SCH 23390 nor the D2 receptor antagonist l-sulpiride injected into the LH affected food intake. These results indicate that the inhibition of dopaminergic function in the LH increases food intake. In conclusion, the present results suggest that pregabalin increases food intake through the inhibition of dopaminergic functions in the LH."

the lateral hypothalamus (LH )Pregabalin increases food intake through dopaminergic systems in the hypothalamus. - PubMed - NCBI

My apologies if you are talking of gabapentin instead of pregabalin. The former is considered the " little brother " of pregabalin/Lyrica Perhaps my above posts should be attached to pregabalin thread issues? Sorry, giddykitty I feel bad. I did not pay attention but realize they both work as a calcium channel blockers Though obviously work in their distinct ways

@metamorphosis12 I am taking Gabapentin, not pregabalin. But it's ok. Interesting to know.

I still am not sure if I gained any weight. I'm going in for bloodwork today. They might check weight too.

I don't think so, but I'm honestly overweight to begin with and don't necessarily notice stuff like that. Plus, I was only on it for a few months, maybe six tops anyway.

It was weight neutral for me.

Weight neutral for me, but I watch my weight like a hawk. I weigh every single day. I'm on a lot, though, it's supposed to be for anxiety, but secondarily it is to curb my alcohol use. I take 2,000 mg/day. Maybe more is better? Happens with some drugs.

Had I stayed on gabapentin, I would have become a moose. Every night I got out of bed to cook. Not worth it. Was supposed to help my anxiety. It didn't.

Yes, I was taken off lorazepam and put on this for my anxiety and panic attacks. I've gained like 25lbs in a little over 6 months....