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Default Sep 08, 2017 at 06:07 PM
  #41
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Stopped by my father's today. He's been living in a delusion since 2001, treatment resistant. He was on an antipsychotic for a month and then said hell no. I asked him questions about anhedonia, how music effects him since he's a music buff, about pleasure, about if he ever feels lonely, or has trouble attaching ideas to emotions at all and he has no problem with any of it. These meds I've taken...
I really vacillate between blaming the meds and blaming the illness....keep in mind you are genetically distinct from your dad....what impacts him might not impact you in the same way, no one in my family has exactly the same outcome.

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Default Sep 08, 2017 at 06:48 PM
  #42
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I really vacillate between blaming the meds and blaming the illness....keep in mind you are genetically distinct from your dad....what impacts him might not impact you in the same way, no one in my family has exactly the same outcome.
It's a striking coincidence that I go on a med, two weeks later it takes away my panic attacks and my emotions never to have them back even when I go off them. There wasn't a steady decline, it was like a light switch, with a subtle difference when I switched from ssri to lamictal. My emotions were all over the place before meds. Me and my father may be different, but we're a hell a lot of alike, genetically, humor, looks, he has psychosis, persecution, delusion. His and my trigger for how it occurred are almost identical even
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Default Sep 08, 2017 at 07:11 PM
  #43
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It's a striking coincidence that I go on a med, two weeks later it takes away my panic attacks and my emotions never to have them back even when I go off them. There wasn't a steady decline, it was like a light switch, with a subtle difference when I switched from ssri to lamictal. My emotions were all over the place before meds. Me and my father may be different, but we're a hell a lot of alike, genetically, humor, looks, he has psychosis, persecution, delusion. His and my trigger for how it occurred are almost identical even
Hmmm maybe you and your dad are more similar than me and my relatives...so you're saying it was lamictal?

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Default Sep 08, 2017 at 07:46 PM
  #44
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Hmmm maybe you and your dad are more similar than me and my relatives...so you're saying it was lamictal?
I felt nothing--nothing on the SSRI Lexapro except manic anger, and then when the depressed and manic episodes started to occur I was then immediately put on lithium, where I still felt anhedonia but I still felt more emotions, even though they were negative emotions like fear and angst, lamictal was more of the same of lithium without the tremors and blood tests. So I never had a chance to tell whether it was the SSRI or Lamictal because the lithium acts quicker than most drugs.
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Default Sep 08, 2017 at 08:51 PM
  #45
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I felt nothing--nothing on the SSRI Lexapro except manic anger, and then when the depressed and manic episodes started to occur I was then immediately put on lithium, where I still felt anhedonia but I still felt more emotions, even though they were negative emotions like fear and angst, lamictal was more of the same of lithium without the tremors and blood tests. So I never had a chance to tell whether it was the SSRI or Lamictal because the lithium acts quicker than most drugs.
There are a lot of anecdotal reports of lexapro doing this......but it's few and far between....I don't think there is research into it yet......

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Default Sep 08, 2017 at 09:15 PM
  #46
I was just reading about Lexapro and anhedonia just now and it's honestly common among nearly all SSRI's I tried Prozac before that and felt the same way. That's what my doctor said. That's why he was reluctant to take me off it. A google search is riddled with connections of ssri's with anhedonia. Interestingly though, I found this random post suggesting that a hyperactive NMDA can cause problems when introduced to an SSRI. It was just a single post and that's all it said. I wonder why that person has that theory...
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Default Sep 08, 2017 at 09:17 PM
  #47
So I need to do dual n back for 20 minutes a day for at least 19 days. I wonder if there is a game that already mimics it so I'm not staring at dots on a screen.
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Default Sep 08, 2017 at 09:20 PM
  #48
What would the behavior of a hyper NMDA person be I wonder.
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Default Sep 08, 2017 at 09:22 PM
  #49
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What would the behavior of a hyper NMDA person be I wonder.
It kills neurons with too much stimulation.....but sz is supposed to have hypofunction so I doubt that's it.....

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Default Sep 08, 2017 at 09:23 PM
  #50
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So I need to do dual n back for 20 minutes a day for at least 19 days. I wonder if there is a game that already mimics it so I'm not staring at dots on a screen.
Lumosity has something but it's pay and not much better.....

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Default Sep 08, 2017 at 09:25 PM
  #51
dude. dude. dude. There are two dual n pack games on my windows phone. There is literally an app for that. What if I remember the past three moves instead? I can do that pretty easily.
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Default Sep 08, 2017 at 09:28 PM
  #52
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dude. dude. dude. There are two dual n pack games on my windows phone. There is literally an app for that. What if I remember the past three moves instead? I can do that pretty easily.
Yes normal people should be able to get up to 5 after training. I can't get past 1 right now.....

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Default Sep 08, 2017 at 09:37 PM
  #53
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Yes normal people should be able to get up to 5 after training. I can't get past 1 right now.....
Ok just got up to two, but still it's rough going for me....

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Default Sep 08, 2017 at 09:39 PM
  #54
First round is done. Day 1.
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Default Sep 08, 2017 at 09:42 PM
  #55
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First round is done. Day 1.
Glad you're giving this a shot

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Default Sep 08, 2017 at 09:43 PM
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Default Sep 08, 2017 at 09:49 PM
  #57
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The reboxetine part was what was interesting but upon a closer look it's contraindicated in bipolar....can't remember are you bipolar or sz? It impacts norepinephrine ....apparently can also reverse AP induced weight gain....talk about a wonder drug if you're not bipolar.....

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Default Sep 08, 2017 at 10:17 PM
  #58
For your short term memory loss, maybe behind the scene of your known mental state something is causing stress on your hippocampus. Usually stress, anxiety, depression cause shrinkage/problems with it. That's what happened with me. Are you experiencing any of those symptoms? My roommate, ironically, has been on Lexapro AND Abilify since before 5 years ago at least. She experiences emotions and she doesn't have memory problems. I'm googling Geodon and memory loss and getting just as many hits as with Abilify. Is there some form of constant stress you're under?

I found this on a site https://bipolar.newlifeoutlook.com/bipolar-memory-loss/ Saying memory cognition can coincide with bipolar...
Quote:
What Parts of Our Memory Are Affected?
Working memory is the area that research shows is most affected by bipolar. It is the short-term storage of information whilst we are performing tasks.
One theory is that people with bipolar experience signaling problems in the prefrontal cortex of the brain. This region has been implicated in planning complex cognitive behavior, including personality, decision-making and social behavior.
Studies show that when the prefrontal cortex does not function properly with the amygdala — which is responsible in the processing of memory, decision-making and emotional reactions — it leads to mood swings. It also disrupts the executive functioning (mental skills that help to get things done) and information processing.
The site also said this on the second page:
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How Can We Help Our Memory Loss?
Research has shown that lithium increases gray matter in the brain, which can improve cognitive function.
We can interrupt the memory loss cycle by reducing our stress.
I know from personal experience Lithium didn't give me memory issues, however I would often find myself lost and confused the first few months on Lamictal.

Are there periods where you have bp symptoms and your memory gets worse and then your symptoms go away and your cognition gets a bit clearer?
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Default Sep 08, 2017 at 10:30 PM
  #59
I don't know what illness I have, only that Geodon helps it. During my only psychosis, that lasted a year, I was hypersexual and suicidally depressed, paranoid, feeling persecuted. I was very hypersexual. Ah the good ol days where simple philosophy could give me deep chills. Anyway, if I wasn't thrown in the hospital then i'd be like my father, still in psychosis. I didn't have any mood swings, it was like I was living in a mixed state. Before the delusion started I was such a rock too. Man i was prepared to go to UofM while holding a full time job, working out every other day, sex, sex sex. I was a machine.

I really don't want to test whether I'd still have a delusion while unable to be manic or depressed. It might be revealing that I was manic depressive on Lexapro though, because that's common with bipolar patients. That would really be telling. My father though is celibate completely. He doesn't do anything like that because he fears he's constantly being watched. He doesn't really read anymore either, that use to be a great source of pleasure in his life. He said it's because of his eye sight but he has reading glasses on his table. He just watches a lot of tv and huddles in his house. He use to gamble. Also, when he was new to the delusion he leased a corvette that cost him dearly. His delusion is grandiose...

Reboxetine not US approved. That's the second med I can't touch now. I'd be interested to learn more about it.
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Default Sep 08, 2017 at 10:34 PM
  #60
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Originally Posted by Day Tripper View Post
For your short term memory loss, maybe behind the scene of your known mental state something is causing stress on your hippocampus. Usually stress, anxiety, depression cause shrinkage/problems with it. That's what happened with me. Are you experiencing any of those symptoms? My roommate, ironically, has been on Lexapro AND Abilify since before 5 years ago at least. She experiences emotions and she doesn't have memory problems. I'm googling Geodon and memory loss and getting just as many hits as with Abilify. Is there some form of constant stress you're under?

I found this on a site https://bipolar.newlifeoutlook.com/bipolar-memory-loss/ Saying memory cognition can coincide with bipolar...

The site also said this on the second page:
I know from personal experience Lithium didn't give me memory issues, however I would often find myself lost and confused the first few months on Lamictal.

Are there periods where you have bp symptoms and your memory gets worse and then your symptoms go away and your cognition gets a bit clearer?

Mostly I'm having anxiety symptoms according to the pdocs miniquizzes......and my thinking was way worse when I started my new job....but it's still not great. I actually read a paper today on grm3 which is the mutation I have....apparently for some mutations treatment actually enhances cognitive impairment this is with any AP. Another grm3 mutation did not have the same effect so there is a genetic component in our response to meds even within the same gene.

Honestly I don't think I get bipolar symptoms to any extent the AP is a pretty good mood stabilizer.....

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