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Old 07-16-2020, 07:49 AM   #11
possum220
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I am sorry that you are going through this TunedOut. You are in my thoughts.

May your doctors give you the right treatment for you.

Take each day as it comes. And yes, chocolate is the best medicine.
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Old 07-23-2020, 03:05 AM   #12
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Will be going to get an MRI and have an IV pump placed in my chest today. When I looked at my records online this morning, the PET scan results included the following:

1. Hypermetabolic left breast mass is consistent with the
patient's known history of breast cancer.
2. Hypermetabolic left axillary lymphadenopathy in the level 1
and level 2 stations consistent with metastatic disease. No
distant metastasis.


So my impression is that the breast cancer is in two lymph nodes (from other parts of the report) and is stage 3 not 4 just as the doctor presumed since I do not have pain in other parts of my body. I was anxious about being in Stage 4 and pretty sure the PET scan says I am not. My chemo starts on Tuesday, the 28th...
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Old 07-30-2020, 06:39 AM   #13
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My chemotherapy was two days ago and I am sleeping all of the time, more than twelve hours a day. I can eat but don't want to eat as much and a couple of times after eating when I felt a little nauseated, I took prochlorperazine maleate 10 mg. In the morning, they gave me dexamethasone 8 mg twice a day which is steroid so it makes me feel jumpy about a half an hour after I take it but the jump feeling only lasts about an hour--I have never liked steriods. Lastly, they gave me Olanzapine 10 mg to prevent nausea and vomiting but I find it interesting that the main use for this drug is "is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life (from WebMD.com)." However, a family member also sent me this:

Chemotherapy-induced acute and delayed nausea or vomiting (high emetic risk [>90%]), preventionLevel of Evidence [A, G]

Data from a randomized, phase 3 study support the use of oral olanzapine (in combination with dexamethasone and palonosetron) for the prevention of acute and delayed chemotherapy-induced nausea and vomiting in chemotherapy-naive patients receiving highly emetogenic chemotherapy RefNavari 2011. Data from a multicenter, randomized, phase 3 study also support the use of oral olanzapine (in combination with triplet antiemetic therapy) for prevention of acute and delayed chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy RefHashimoto 2020. Data from a randomized, phase 2 study that included chemotherapy-naive patients who received moderately and highly emetogenic chemotherapy regimens also suggest that oral olanzapine (in combination with dexamethasone and palonosetron) may be beneficial for prevention of acute and delayed nausea and vomiting RefNavari 2007.

Based on antiemetic guidelines from the American Society of Clinical Oncology (ASCO), oral olanzapine may be used for prevention of acute and delayed chemotherapy-induced nausea and vomiting (in combination with antiemetics used for high emetic risk agents) in patients receiving highly emetogenic chemotherapy RefASCO [Hesketh 2017].

https://online.lexi.com/lco/graphics/minus.png Chemotherapy-induced breakthrough nausea or vomiting, treatmentLevel of Evidence [A, G]

Data from a randomized, controlled, phase 3 study support the use of oral olanzapine in the management of breakthrough nausea and vomiting associated with highly emetogenic chemotherapy RefNavari 2013.

Based on antiemetic guidelines from the ASCO, oral olanzapine may be used for management of breakthrough nausea and vomiting (if olanzapine was not part of the standard prophylactic regimen) RefASCO [Hesketh 2017].

I will continue to take all the drugs as prescribed because I dislike throwing up which I am told is very common with the chemotherapy I am on:
Doxorubicin and cyclophosphamide
Apparently, I am quite poisonous for about four days, they said even my saliva is poisonous so no kissing or anything like that for a few days. If I were to throw up (crossing my fingers and taking all my meds so i don't), if someone cleans it they should use a mask and gloves! and if it isn't cleaned, when it dries, it could release toxins in the air. I won't go into the full precaution list I was given but they said to even be careful about petting cats and dogs and don't garden (there are germs in the dirt).
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Old 07-30-2020, 06:45 AM   #14
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Prayers for you that the chemo is working and you make a full recovery.
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Old 07-30-2020, 11:07 AM   #15
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Same here. My sis recovered from stage 4 ovarian cancer, so anything is possible.
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Old 07-30-2020, 11:23 AM   #16
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Tisha and Travelinglady
Your prayers are really appreciated and I will pray for both of you too! We need all the help we can get.
And PS when I did my walk this morning, I noticed that the lymph node that helped identify my condition (I had a mammography in December so this thing appeared quickly) was no longer sore and the size has already shrunk.

Last edited by TunedOut; 07-30-2020 at 11:36 AM..
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Old 07-30-2020, 05:18 PM   #17
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Thank you for the updates. You are courageous! And that's not something I say easily, because life is rough for all of us. But seriously, you're going above and beyond.

btw, I have noticed that there are a number of AP's that are used to combat nausea.
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Old 07-31-2020, 06:16 PM   #18
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♥️♥️♥️♥️

Thinking of you. You are a very brave person with much strength Tuned Out.
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Old 08-01-2020, 03:17 AM   #19
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Quote:
Originally Posted by Discombobulated View Post
♥️♥️♥️♥️

Thinking of you. You are a very brave person with much strength Tuned Out.
Thanks so much, you have always encouraged me in so many ways. First round of chemo wasn't that bad. Still have my hair but don't need to shave as much anymore. It must be a cumulative thing where you feel it the most at the end. My next poisoning is scheduled for August 11th. Going on as usual in the meantime.

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Old 08-08-2020, 02:35 AM   #20
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Though I am doing OK, there are some small chemotherapy effects that I am dealing with: feeling more tired, sweating a lot when I sleep (but no fever, I have been told to monitor for a fever everyday), during my walks I have been getting charlie horses and my leg muscles are sore during and after, drier skin including cracking at the corner of my mouth and some sore bumps on my tongue. They gave me a mouthwash of one part: Malox, Lidocane and Diphenhydramine to swish in my mouth for the sore bumps that they said would appear. So apparently, the effects of the chemo stay with you. Still have my hair though and can't say that I am wanting to eat much differently than before (they said I might not want to eat the same way as before) other than I don't crave coffee anymore (but still have one or two cups a day). Given that the Malox in the mouthwash is an antacid, think I might pick up some alkaline water. That might be soothing for my mouth.

While I am resting more, I am still cooking and doing many of the things around the house I have always done. One hiccup that occurred is about a week ago, our waterbed sprung a small leek so my sleeping arrangements haven't been optimal but the new mattress came and my husband will be setting it up today. Should be all warmed up by tomorrow.
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